Acute Anaemia: A Challenging Diagnosis
  • Rui Costa
    Internal Medicine Department, Hospital São Francisco Xavier, Lisbon, Portugal
  • Catarina Araújo Faria
    Internal Medicine Department, Hospital São Francisco Xavier, Lisbon, Portugal
  • Catarina Sofia Nunes
    Transfusion Medicine Department, Hospital São Francisco Xavier, Lisboa, Portugal
  • Filipa Ferreira
    Oncology Department, Hospital São Francisco Xavier, Lisboa, Portugal
  • Rui Cunha
    Intensive Care Medicine Department, Hospital São Francisco Xavier, Lisboa, Portugal
  • Inês Egídio Sousa
    Internal Medicine Department, Hospital São Francisco Xavier, Lisboa, Portugal
  • Inês Ferreira
    Internal Medicine Department, Hospital São Francisco Xavier, Lisboa, Portugal

Keywords

Acute anaemia, paraneoplastic syndrome, schistocytes, thrombotic microangiopathies

Abstract

Acute anaemia is characterized by a reduction in the number of red blood cells, haemoglobin levels or haematocrit. By far the most common aetiology is haemorrhage, but in its absence other less frequent causes should be considered.
The authors present the case of a 42-year-old man with a diagnosis of glucose-6-phosphate deficiency and progressing gastric signet ring cell carcinoma, who was admitted to the internal medicine department for symptomatic back pain control. During his hospitalization, the patient developed acute anaemia with schistocytes on peripheral blood smear with no concurrent hyperbilirubinaemia or decreased haptoglobin. Bone metastatic disease was documented. The case was revised with the transfusion medicine department and malignancy-associated microangiopathic haemolytic anaemia (Ma-MAHA) was suggested. The patient was transferred to the oncology department and later discharged, dying at home shortly afterwards.

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References

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    Published: 2018-09-18
    Issue: Vol 5 No 9 (view)


    How to cite:
    1.
    Costa R, Faria CA, Nunes CS, Ferreira F, Cunha R, Sousa IE, Ferreira I. Acute Anaemia: A Challenging Diagnosis. EJCRIM 2018;5 doi:10.12890/2018_000956.

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