Is Aphtous Oral Ulceration Biopsy Always Useless?
  • Yohan N'Guyen
    Internal Medicine Department, Infective Diseases and Clinical Immunology, Robert Debré Hospital, Reims, France
  • Amélie Servettaz
    Internal Medicine Department, Infective Diseases and Clinical Immunology, Robert Debré Hospital, Reims, France
  • Florent Ehrhard
    Hepatology and Gastroenterology Department, Robert Debré Hospital, Reims, France
  • Firouze Bani-Sadr
    Internal Medicine Department, Infective Diseases and Clinical Immunology, Robert Debré Hospital, Reims, France
  • Michel Pluot
    Pathological Anatomy Laboratory, Robert Debré Hospital, Reims, France

Abstract

Objective: To report a case of Behc?et’s disease whose diagnosis was only confirmed thanks to an oral aphthous lesion biopsy.

Materials and methods: Conventional histopathological analysis of a biopsy of an aphthous oral lesion that had appeared two days previously.

Results: A small vein vasculitis with eosinophil and neutrophil granulocytes was evidenced.

Conclusion: The presence of a small vein vasculitis was here strongly in favour of Behc?et's disease, whereas such a diagnosis was not confirmed according to the International Study Group’s criteria.

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References

  • Scully C. Aphthous ulceration, N. Engl. J. Med.2006;355:165–172.
  • International Study Group for Behçet’s Disease. Criteria for diagnosis of Behcet’s disease, Lancet 1990;335:1078–1080.
  • Chen KR, Kahawara Y, Miyakawa S, Nishikawa T. Cutaneous vasculitis in Behcet's disease: a clinical and histopathologic study of 20 patients, J. Am. Acad. Dermatol. 1997;36:689–696.
  • Melikoglu M, Kural-Seyahi E, Tascilar K, Yazici H. The unique features of vasculitis in Behçet’s syndrome, Clin. Rev. Allergy Immunol. 2008;35:40–46.
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    Published: 2014-06-13
    Issue: Vol. 1 (2014) (view)


    How to cite:
    1.
    N’Guyen Y, Servettaz A, Ehrhard F, Bani-Sadr F, Pluot M. Is Aphtous Oral Ulceration Biopsy Always Useless?. EJCRIM 2014;1 doi:10.12890/2014_000086.

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