Sudden cardiac arrest as first manifestation of malignant mitral valve prolapse in a young patient: a case report and review of the literature
  • Leila Bigdelu
    Cardiovascular Medicine Division, Vascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  • Zouheir Bitar
    Critical Care Unit, Internal Medical Department, Ahmadi Hospital-Kuwait Oil Company, Kuwait
  • Ossama Maadarani
    Critical Care Unit, Internal Medical Department, Ahmadi Hospital-Kuwait Oil Company, Kuwait


Mitral valve prolapse, malignant phenotype, sudden cardiac death


Mitral valve prolapse (MVP) is a primary valvular disease of the mitral valve with a prevalence of 2.4% of the general population. Valve abnormalities range from simple fibroelastic deficiency of the leaflets to diffuse myxomatous degenerative changes. MVP is a usually a benign condition. However, the scattered reports of sudden cardiac death in patients with MVP in the absence of severe mitral insufficiency or coronary artery disease suggest the existence of a malignant phenotype of MVP. We report a case of a young female who survived life-threatening arrhythmias and cardiac arrest and was found to have characteristic features of the malignant phenotype of MVP and had an implantable cardioverter defibrillator as a secondary prevention.



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    Published: 2024-04-03
    Issue: 2024: LATEST ONLINE (view)

    How to cite:
    Bigdelu L, Bitar Z, Maadarani O. Sudden cardiac arrest as first manifestation of malignant mitral valve prolapse in a young patient: a case report and review of the literature. EJCRIM 2024;11 doi:10.12890/2024_004505.

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