Angina pectoris as a manifestation of ALCAPA syndrome in a 20-year-old female: a case report and review of literature
  • Leila Bigdelu
    Cardiovascular Medicine Division, Vascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  • Ossama Maadarani
    Consultant internal medicine and cardiology
  • Ali Azari
    Cardiovascular Medicine Division, Vascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  • Ali Heidari-Bakavoli
    Department of Imaging, Razavi Hospital, Mashhad, Iran
  • Zouheir Bitar
    Critical Care Unit, Internal Medical Department, Ahmadi Hospital (KOC), Kuwait

Keywords

ALCAPA, echocardiography, angina pectoris

Abstract

Anomalous left coronary artery from the pulmonary artery (ALCAPA) is considered a rare congenital heart disease where the take-off of the left coronary artery abnormally originates from the pulmonary artery instead of left aortic sinus. It is associated with a high mortality rate in the first year of life and sudden death in adults if left untreated. We report an adult form of ALCAPA syndrome in a 20-year-old female who presented with anginal pain for the previous few months. Unfortunately, the patient was hesitant to have surgery at the time.

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References

  • Fernandes ED, Kadivar H, Hallman GL, Reul GJ, Ott DA, Cooley DA. Congenital malformations of the coronary arteries: the Texas Heart Institute experience. Ann Thorac Surg 1992;54:732–740.
  • Keith JD. The anomalous origin of the left coronary artery from the pulmonary artery. Br Heart J 1959;21:149–161.
  • Bland EF, White PD, Garland J. Congenital anomalies of coronary arteries: report of an unusual case associated with cardiac hypertrophy. Am Heart J 1933;8:787–801.
  • Yau JM, Singh R, Halpern EJ, Fischman D. Anomalous origin of the left coronary artery from the pulmonary artery in adults: a comprehensive review of 151 adult cases and a new diagnosis in a 53-year-old woman. Clin Cardiol 2011;34:204–210.
  • Chang RR, Allada V. Electrocardiographic and echocardiographic features that distinguish anomalous origin of the left coronary artery from pulmonary artery from idiopathic dilated cardiomyopathy. Pediatr Cardiol 200;22:3-10.
  • Kayalar N, Burkhart HM, Dearani JA, Cetta F, Schaff HV. Congenital coronary anomalies and surgical treatment. Congenit Heart Dis 2009;4:239–251.
  • Lotman E-M, Karu K, Mikkel M, Elmet M. Late adult presentation of ALCAPA syndrome: need for a new clinical classification? A case report and literature overview. Eur Heart J Case Rep 2020;4:1–5.
  • Xiao Y, Jin M, Han L, Ding W, Zheng J, Sun C, et al. Two congenital coronary abnormalities affecting heart function: anomalous origin of the left coronary artery from the pulmonary artery and congenital left main coronary artery atresia. Chin Med J (Engl) 2014;127:3724–3731.
  • Yau JM, Singh R, Halpern EJ, Fischman D. Anomalous origin of the left coronary artery from the pulmonary artery in adults: a comprehensive review of 151 adult cases and a new diagnosis in a 53-year-old woman. Clin Cardiol 2011;34:204–210.
  • Yu Y, Wang Q-S, Wang X-F, Sun J, Yu L-W, Ding M, et al. Diagnostic value of echocardiography on detecting the various types of anomalous origin of the left coronary artery from the pulmonary artery. J Thorac Dis 2020;12:319–328.
  • Drinkovic N, Margetic E, Smalcelj A, Brida V. Echocardiographic diagnosis of anomalous origin of the left coronary artery from the pulmonary artery. Eur J Echocardiogr 2008;9:309–310.
  • Yang Y-L, Nanda NC. Wang X-F, Xie MX, Lu Q, He L, et al. Echocardiographic diagnosis of anomalous origin of the left coronary artery from the pulmonary artery. Echocardiography 2007;24:405–411.
  • Duan X, Yu T, Wang F, Liu H, Sun J, Zhai R. Anomalous origin of the left coronary artery from the pulmonary artery in infants: imaging findings and clinical implications of cardiac computed tomography. J Comput Assist Tomogr 2015;39:189–195.
  • Goo HW, Seo D-M, Yun T-J, Park J-J, Park I-S, Ko JK, et al. Coronary artery anomalies and clinically important anatomy in patients with congenital heart disease: multislice CT findings. Pediatr Radiol 2009;39:265–273.
  • Horisaki T, Yamashita T, Yokoyama H, Urasawa K, Kitabatake A. Three-dimensional reconstruction of computed tomographic images of anomalous origin of the left main coronary artery from the pulmonary trunk in an adult. Am J Cardiol 2003;92:898–899.
  • Shen Q, Yao Q, Hu X. Anomalous origin of the left coronary artery from the pulmonary artery in children: diagnostic use of multidetector computed tomography. Pediatr Radiol 2016;46:1392–1398.
  • Peña E, Nguyen ET, Merchant N, Dennie C. ALCAPA syndrome: not just a pediatric disease. Radiographics 2009;29:553–565.
  • Dodge-Khatami A, Mavroudis C, Backer CL. Anomalous origin of the left coronary artery from the pulmonary artery: collective review of surgical therapy. Ann Thorac Surg 2002;74:946–955.
  • Lange R, Vogt M, Hörer J, Cleuziou J, Menzel A, Holper K, et al. Long-term results of repair of anomalous origin of the left coronary artery from the pulmonary artery. Ann Thorac Surg 2007;83:1463–1471.

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    Published: 2023-06-26
    Issue: 2023: Vol 10 No 7 (view)

    How to cite:
    1.
    Bigdelu L, Maadarani O, Azari A, Heidari-Bakavoli A, Bitar Z. Angina pectoris as a manifestation of ALCAPA syndrome in a 20-year-old female: a case report and review of literature. EJCRIM 2023;10 doi:10.12890/2023_003962.

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