Idiopathic bilateral pulmonary vein thrombosis
  • Adeel Nasrullah
    Division of Pulmonology and Critical Care, Allegheny Health Network, Pittsburgh, USA
  • Muhammad Ibraiz Bilal
    Department of Internal Medicine, Allegheny Health Network, Pittsburgh, USA
  • Khalid Malik
    Division of Pulmonology and Critical Care, Allegheny Health Network, Pittsburgh, USA
  • Briana DiSilvio
    Division of Pulmonology and Critical Care, Allegheny Health Network, Pittsburgh, USA
  • Tariq Cheema
    Division of Pulmonology and Critical Care, Allegheny Health Network, Pittsburgh, USA

Keywords

Pulmonary vein thrombosis, idiopathic, anticoagulation

Abstract

A 52-year-old female with a history of chronic lymphoedema and untreated deep vein thrombosis, presented with non-specific right-sided chest pain. A CT angiogram confirmed bilateral inferior pulmonary vein thromboses (PVT). A comprehensive hypercoagulable workup and age-appropriate cancer screening were unremarkable; the lack of associated risk factors confirmed idiopathic PVT. The management strategy of systemic anticoagulation with apixaban and multidisciplinary follow-up underscores the treatment challenges of rare presentations. This case accentuates the importance of considering PVT in differential diagnoses of atypical chest pain and contributes valuable insights into the diagnosis, understanding and management of this uncommon condition.

VIEW THE ENTIRE ARTICLE

References

  • Ngo D, Aftab G, Madhavan A, Bukhari A. Idiopathic pulmonary vein thrombosis treated with apixaban. Respirol Case Rep 2021;9:e00803.
  • Selvidge SD, Gavant ML. Idiopathic pulmonary vein thrombosis: detection by CT and MR imaging. AJR Am J Roentgenol 1999;172:1639–1641.
  • Komatsu S, Kamata T, Imai A, Miyaji K, Ohara T, Takewa M, et al. Idiopathic pulmonary vein thrombosis complicated with old myocardial infarction detected by multidetector row computed tomography. J Cardiol Cases 2011;3:e94–e97.
  • Goddard SA, Tran DQ, Chan MF, Honda MN, Weidenhaft MC, Triche BL. Pulmonary vein thrombosis in COVID-19. Chest 2021;159:e361–e364.
  • Mumoli N, Cei M. Idiopathic pulmonary vein thrombosis. J Emerg Med 2012;42:182–183.
  • Alexander GR, Reddi A, Reddy D. Idiopathic pulmonary vein thrombosis: a rare cause of massive hemoptysis. Ann Thorac Surg 2009;88:281–283.
  • Garcia MJ, Rodriguez L, Vandervoort P. Pulmonary vein thrombosis and peripheral embolization. Chest 1996;109:846–847.
  • Nagahiro I, Horton M, Wilson M, Bennetts J, Spratt P, Glanville AR. Pulmonary vein thrombosis treated successfully by thrombectomy after bilateral sequential lung transplantation: report of a case. Surg Today 2003;33:282–284.
  • Ohtaka K, Hida Y, Kaga K, Kato T, Muto J, Nakada-Kubota R, et al. Thrombosis in the pulmonary vein stump after left upper lobectomy as a possible cause of cerebral infarction. Ann Thorac Surg 2013;95:1924–1928.
  • Rana MA, Tilbury N, Kumar Y, Ahmad H, Naser K, Mady AF, et al. Idiopathic pulmonary vein thrombus extending into left atrium: a case report and review of the literature. Case Rep Med 2016;2016:3528393.
  • Schulman LL, Anandarangam T, Leibowitz DW, Ditullio MR, McGregor CC, Galantowicz ME, et al. Four-year prospective study of pulmonary venous thrombosis after lung transplantation. J Am Soc Echocardiogr 2001;14:806–812.
  • Selvidge SD, Gavant ML. Idiopathic pulmonary vein thrombosis: detection by CT and MR imaging. R Am J Roentgenol 1999;172:1639–1641.
  • Chaaya G, Vishnubhotla P. Pulmonary vein thrombosis: a recent systematic review. Cureus 2017;9:e993.
  • Barreiro TJ, Kollipara VK, Gemmel DJ. Idiopathic pulmonary vein thrombosis? Respirol Case Rep 2018;6:e00277. doi: 10.1002/rcr2.277
  • Kim NH, Roldan CA, Shively BK. Pulmonary vein thrombosis. Chest 1993;104:624–626.
  • Stevens SM, Woller SC, Kreuziger LB, Bounameaux H, Doerschug K, Geersing G-J, et al. Executive summary: antithrombotic therapy for VTE disease: second update of the CHEST Guideline and Expert Panel Report. Chest 2021;160:e545–e608.

    • Views: 223
    HTML downloads: 30
    PDF downloads: 173

    Published: 2024-01-26
    Issue: 2024: Vol 11 No 2 (view)

    How to cite:
    1.
    Nasrullah A, Bilal MI, Malik K, DiSilvio B, Cheema T. Idiopathic bilateral pulmonary vein thrombosis. EJCRIM 2024;11 doi:10.12890/2024_004291.

    Most read articles by the same author(s)