Partial Seizures as the First Manifestation of Primary Angiitis of the Central Nervous System

  • Elisa Brauns Service de Médecine Interne, CHU Erasme, Brussels, Belgium
  • Sophie Schuind Service de Neurochirurgie, CHU Erasme, Brussels, Belgium
  • Laetitia Lebrun Service d’Anatomo-pathologie, CHU Erasme, Brussels, Belgium
  • Valentine Inthasot Service de Médecine Interne, Hôpital d’Ixelles, Brussels, Belgium
  • Frédéric Vandergheynst Service de Médecine Interne, CHU Erasme, Brussels, Belgium

Abstract

A young woman presented with initial epileptic seizures and multiple ‘mass-like’ lesions seen on computed tomography and magnetic resonance imaging. Given this presentation and her past medical history, a cerebral biopsy was performed to rule out malignancy, but showed a necrotizing cerebral vasculitis. We describe this case to reinforce the view that primary central nervous system vasculitis (PCNSV) should be considered in the differential diagnosis of a cerebral mass, even if uncommon.

References

  • Salvarani C, Brown RD, Christianson TJ, Miller DV, Giannini C, Huston J, et al. An update of the Mayo Clinic cohort of patients with adult primary central nervous system vasculitis: description of 163 patients. Medicine 2015;94:e738.

  • Salvarani C, Brown RD, Hunder GG. Adult primary central nervous system vasculitis. Lancet 2012;380:767–77.

  • Molloy ES, Singhal AB, Calabrese LH. Tumour-like mass lesion: an under-recognised presentation of primary angiitis of the central nervous system. Ann Rheum Dis 2008;67:1732–35.

  • Kadkhodayan Y, Alreshaid A, Moran CJ, Cross DT, Powers WJ, Derdeyn CP. Primary angiitis of the central nervous system at conventional angiography. Radiology 2004;233:878–82.

  • Miller DV, Salvarani C, Hunder GG, Brown RD, Parisi JE, Christianson TJ, et al. Biopsy findings in primary angiitis of the central nervous system. Am J Surg Pathol 2009;33:35–43.
  • Published: 2017-12-27

    Issue: Vol 5 No 2 (view)

    Section: Articles

    How to cite:
    Brauns, E., Schuind, S., Lebrun, L., Inthasot, V., & Vandergheynst, F. (2017). Partial Seizures as the First Manifestation of Primary Angiitis of the Central Nervous System. European Journal of Case Reports in Internal Medicine, 5(2). https://doi.org/https://doi.org/10.12890/2017_000784